Primary malignant tumors of the nasal septum
- First report:Gibs in 1902
- 稀な腫瘍でnasal cavity原発の9%程度
- 2000年までに300弱の報告がある
- 男女差なし
- 40-50歳代が多いが、30歳の報告もある
- Squamous cell carcinomaが最多
- 喫煙と関連?
Initial symptoms
- Nasal airway obstructions 40%
- Epistaxis 27%
- Rhinorrhea 23%
- Nasal pain 21%
- Sensation of nasal mass 14%
- Septal ulceration 13%
- Other 19%
- None noted 8%
REFFERENCES
(1) Young JR.
Malignant tumours of the nasal septum.
J Laryngol Otol.
1979 Aug;93(8):817-33.
(2) Beatty CW, et.al.
Carcinoma of the nasal septum:
experience with 85 cases.
Otolaryngol Head Neck Surg.
1982 Jan- Feb;90(1):90-4.
Carcinoma of the nasal septum |
|
(1) |
(2) |
Squamous cell carcinoma
Malignant melanoma
Transitional cell carcinoma
Adenocarcinoma
Anaplastic carcinoma
Reticulum cell sarcoma
Mucoepidermoid carcinoma
Plasmacytoma
Adenocystic carcinoma
Mixed(SCC+Adeno)
Basal cell
Total |
23
5
5
3
2
2
1
1
1
-
-
43 |
58
7
-
12
2
1
1
2
1
85 |
転移:30%
sinuses, brain, orbid, cervical nodes,
lung, abdomen
治療:operation
radiotherapy (50-55Gy)
chemotherapy(5-FU, PEP, CDDP, CBDCA)
5年生存率:58 - 68%?
|