症例5 50歳代 女性
診断:鼻中隔扁平上皮癌




組織学第2版 文光堂



Primary malignant tumors of the nasal septum
  • First report:Gibs in 1902
  • 稀な腫瘍でnasal cavity原発の9%程度
  • 2000年までに300弱の報告がある 
  • 男女差なし
  • 40-50歳代が多いが、30歳の報告もある
  • Squamous cell carcinomaが最多
  • 喫煙と関連?

Initial symptoms

  • Nasal airway obstructions 40%
  • Epistaxis 27%
  • Rhinorrhea 23%
  • Nasal pain 21%
  • Sensation of nasal mass 14%
  • Septal ulceration 13%
  • Other 19%
  • None noted 8%

REFFERENCES

(1) Young JR.
Malignant tumours of the nasal septum.
J Laryngol Otol.
1979 Aug;93(8):817-33.
(2) Beatty CW, et.al.
Carcinoma of the nasal septum:
experience with 85 cases.
Otolaryngol Head Neck Surg.
1982 Jan- Feb;90(1):90-4.

Carcinoma of the nasal septum
(1) (2)
Squamous cell carcinoma
Malignant melanoma
Transitional cell carcinoma
Adenocarcinoma
Anaplastic carcinoma
Reticulum cell sarcoma
Mucoepidermoid carcinoma
Plasmacytoma
Adenocystic carcinoma
Mixed(SCC+Adeno)
Basal cell
Total
23
5
5
3
2
2
1
1
1
-
-
43
58
7
-
12
2

1

1
2
1
85


転移:30%
sinuses, brain, orbid, cervical nodes,
lung, abdomen
治療:operation
radiotherapy (50-55Gy)
chemotherapy(5-FU, PEP, CDDP, CBDCA)

5年生存率:58 - 68%?

・症例提示へ

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